Rapid modeling of cooperating genetic events in cancer through somatic genome editing
Cancer is a multistep process that involves mutations and other alterations in oncogenes and tumor suppressor genes1. Genome sequencing studies have identified a large collection of genetic alterations that occur in human cancers2–4. However, the determination of which mutations are causally related...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292871/ |