Lead Clinical and Preclinical Antimalarial Drugs Can Significantly Reduce Sporozoite Transmission to Vertebrate Populations

To achieve malarial elimination, we must employ interventions that reduce the exposure of human populations to infectious mosquitoes. To this end, numerous antimalarial drugs are under assessment in a variety of transmission-blocking assays which fail to measure the single crucial criteria of a succ...

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Bibliographic Details
Main Authors: Upton, L. M., Brock, P. M., Churcher, T. S., Ghani, A. C., Gething, P. W., Delves, M. J., Sala, K. A., Leroy, D., Sinden, R. E., Blagborough, A. M.
Format: Online
Language:English
Published: American Society for Microbiology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291391/