ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells

ILDR1 null mice, a model of human deafness DFNB42, show structural aberrations of tricellular tight junctions and degeneration of auditory hair cells

In the mammalian inner ear, bicellular and tricellular tight junctions (tTJs) seal the paracellular space between epithelial cells. Tricellulin and immunoglobulin-like (Ig-like) domain containing receptor 1 (ILDR1, also referred to as angulin-2) localize to tTJs of the sensory and non-sensory epithe...

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Bibliographic Details
Main Authors: Morozko, Eva L., Nishio, Ayako, Ingham, Neil J., Chandra, Rashmi, Fitzgerald, Tracy, Martelletti, Elisa, Borck, Guntram, Wilson, Elizabeth, Riordan, Gavin P., Wangemann, Philine, Forge, Andrew, Steel, Karen P., Liddle, Rodger A., Friedman, Thomas B., Belyantseva, Inna A.
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291242/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291242/

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