IL-12 stimuli during ex vivo expansion not only prevents the upregulation of PD1 on tumor infiltrating adoptively transferred T cells but also on endogenous TILs which results in effective tumor regression

Bibliographic Details
Main Authors: Diaz-Montero, C Marcela, Yang, Yu, Rayman, Patricia A, Montero, Alberto, Tannenbaum, Charlie, Finke, James
Format: Online
Language:English
Published: BioMed Central 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288377/