ARTD1-induced poly-ADP-ribose formation enhances PPARγ ligand binding and co-factor exchange

ARTD1-induced poly-ADP-ribose formation enhances PPARγ ligand binding and co-factor exchange

PPARγ-dependent gene expression during adipogenesis is facilitated by ADP-ribosyltransferase D-type 1 (ARTD1; PARP1)-catalyzed poly-ADP-ribose (PAR) formation. Adipogenesis is accompanied by a dynamic modulation of the chromatin landscape at PPARγ target genes by ligand-dependent co-factor exchange....

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Bibliographic Details
Main Authors: Lehmann, Mareike, Pirinen, Eija, Mirsaidi, Ali, Kunze, Friedrich A., Richards, Peter J., Auwerx, Johan, Hottiger, Michael O.
Format: Online
Language:English
Published: Oxford University Press 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288160/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288160/

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