Decreased deformability of lymphocytes in chronic lymphocytic leukemia

This paper reports the first study of stiffness/deformability changes of lymphocytes in chronic lymphocytic leukemia (CLL) patients, demonstrating that at the single cell level, leukemic metastasis progresses are accompanied by biophysical property alterations. A microfluidic device was utilized to...

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Bibliographic Details
Main Authors: Zheng, Yi, Wen, Jun, Nguyen, John, Cachia, Mark A., Wang, Chen, Sun, Yu
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287721/