Reconstructing each cell's genome within complex microbial communities—dream or reality?

As the vast majority of microorganisms have yet to be cultivated in a laboratory setting, access to their genetic makeup has largely been limited to cultivation-independent methods. These methods, namely metagenomics and more recently single-cell genomics, have become cornerstones for microbial ecol...

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Bibliographic Details
Main Authors: Clingenpeel, Scott, Clum, Alicia, Schwientek, Patrick, Rinke, Christian, Woyke, Tanja
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287102/