Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains

The Type VII protein secretion system, found in Gram-positive bacteria, secretes small proteins, containing a conserved W-x-G amino acid sequence motif, to the growth medium. Staphylococcus aureus has a conserved Type VII secretion system, termed Ess, which is dispensable for laboratory growth but r...

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Bibliographic Details
Main Authors: Kneuper, Holger, Cao, Zhen Ping, Twomey, Kate B, Zoltner, Martin, Jäger, Franziska, Cargill, James S, Chalmers, James, van der Kooi-Pol, Magdalena M, van Dijl, Jan Maarten, Ryan, Robert P, Hunter, William N, Palmer, Tracy
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285178/