Coxiella burnetii lipopolysaccharide blocks p38α-MAPK activation through the disruption of TLR-2 and TLR-4 association

Coxiella burnetii lipopolysaccharide blocks p38α-MAPK activation through the disruption of TLR-2 and TLR-4 association

To survive in macrophages, Coxiella burnetii hijacks the activation pathway of macrophages. Recently, we have demonstrated that C. burnetii, via its lipopolysaccharide (LPS), avoids the activation of p38α-MAPK through an antagonistic engagement of Toll-like receptor (TLR)-4. We investigated the fine...

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Bibliographic Details
Main Authors: Conti, Filippo, Boucherit, Nicolas, Baldassarre, Veronica, Trouplin, Virginie, Toman, Rudolf, Mottola, Giovanna, Mege, Jean-Louis, Ghigo, Eric
Format: Online
Language:English
Published: Frontiers Media S.A. 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285172/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285172/

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