Thyrotropin and Obesity: Increased Adipose Triglyceride Content Through Glycerol-3-Phosphate Acyltransferase 3

Epidemiological evidence indicates that thyrotropin (TSH) is positively correlated with the severity of obesity. However, the mechanism remains unclear. Here, we show that TSH promoted triglyceride (TG) synthesis in differentiated adipocytes in a thyroid hormone-independent manner. Mice with subclin...

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Bibliographic Details
Main Authors: Ma, Shizhan, Jing, Fei, Xu, Chao, Zhou, Lingyan, Song, Yongfeng, Yu, Chunxiao, Jiang, Dongqing, Gao, Ling, Li, Yujie, Guan, Qingbo, Zhao, Jiajun
Format: Online
Language:English
Published: Nature Publishing Group 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284501/