Hemagglutinin-based polyanhydride nanovaccines against H5N1 influenza elicit protective virus neutralizing titers and cell-mediated immunity

H5N1 avian influenza is a significant global concern with the potential to become the next pandemic threat. Recombinant subunit vaccines are an attractive alternative for pandemic vaccines compared to traditional vaccine technologies. In particular, polyanhydride nanoparticles encapsulating subunit...

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Bibliographic Details
Main Authors: Ross, Kathleen A, Loyd, Hyelee, Wu, Wuwei, Huntimer, Lucas, Ahmed, Shaheen, Sambol, Anthony, Broderick, Scott, Flickinger, Zachary, Rajan, Krishna, Bronich, Tatiana, Mallapragada, Surya, Wannemuehler, Michael J, Carpenter, Susan, Narasimhan, Balaji
Format: Online
Language:English
Published: Dove Medical Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284014/