No Evidence for Genome-Wide Interactions on Plasma Fibrinogen by Smoking, Alcohol Consumption and Body Mass Index: Results from Meta-Analyses of 80,607 Subjects

Plasma fibrinogen is an acute phase protein playing an important role in the blood coagulation cascade having strong associations with smoking, alcohol consumption and body mass index (BMI). Genome-wide association studies (GWAS) have identified a variety of gene regions associated with elevated pla...

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Main Authors: Baumert, Jens, Huang, Jie, McKnight, Barbara, Sabater-Lleal, Maria, Steri, Maristella, Chu, Audrey Y., Trompet, Stella, Lopez, Lorna M., Fornage, Myriam, Teumer, Alexander, Tang, Weihong, Rudnicka, Alicja R., Mälarstig, Anders, Hottenga, Jouke-Jan, Kavousi, Maryam, Lahti, Jari, Tanaka, Toshiko, Hayward, Caroline, Huffman, Jennifer E., Morange, Pierre-Emmanuel, Rose, Lynda M., Basu, Saonli, Rumley, Ann, Stott, David J., Buckley, Brendan M., de Craen, Anton J. M., Sanna, Serena, Masala, Marco, Biffar, Reiner, Homuth, Georg, Silveira, Angela, Sennblad, Bengt, Goel, Anuj, Watkins, Hugh, Müller-Nurasyid, Martina, Rückerl, Regina, Taylor, Kent, Chen, Ming-Huei, de Geus, Eco J. C., Hofman, Albert, Witteman, Jacqueline C. M., de Maat, Moniek P. M., Palotie, Aarno, Davies, Gail, Siscovick, David S., Kolcic, Ivana, Wild, Sarah H., Song, Jaejoon, McArdle, Wendy L., Ford, Ian, Sattar, Naveed, Schlessinger, David, Grotevendt, Anne, Franzosi, Maria Grazia, Illig, Thomas, Waldenberger, Melanie, Lumley, Thomas, Tofler, Geoffrey H., Willemsen, Gonneke, Uitterlinden, André G., Rivadeneira, Fernando, Räikkönen, Katri, Chasman, Daniel I., Folsom, Aaron R., Lowe, Gordon D., Westendorp, Rudi G. J., Slagboom, P. Eline, Cucca, Francesco, Wallaschofski, Henri, Strawbridge, Rona J., Seedorf, Udo, Koenig, Wolfgang, Bis, Joshua C., Mukamal, Kenneth J., van Dongen, Jenny, Widen, Elisabeth, Franco, Oscar H., Starr, John M., Liu, Kiang, Ferrucci, Luigi, Polasek, Ozren, Wilson, James F., Oudot-Mellakh, Tiphaine, Campbell, Harry, Navarro, Pau, Bandinelli, Stefania, Eriksson, Johan, Boomsma, Dorret I., Dehghan, Abbas, Clarke, Robert, Hamsten, Anders, Boerwinkle, Eric, Jukema, J. Wouter, Naitza, Silvia, Ridker, Paul M., Völzke, Henry, Deary, Ian J., Reiner, Alexander P., Trégouët, David-Alexandre, O'Donnell, Christopher J., Strachan, David P., Peters, Annette, Smith, Nicholas L.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281156/