A Versatile Scaffold Contributes to Damage Survival via Sumoylation and Nuclease Interactions

DNA repair scaffolds mediate specific DNA and protein interactions in order to assist repair enzymes in recognizing and removing damaged sequences. Many scaffold proteins are dedicated to repairing a particular type of lesion. Here, we show that the budding yeast Saw1 scaffold is more versatile. It...

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Bibliographic Details
Main Authors: Sarangi, Prabha, Altmannova, Veronika, Holland, Cory, Bartosova, Zdenka, Hao, Fanfan, Anrather, Dorothea, Ammerer, Gustav, Lee, Sang Eun, Krejci, Lumir, Zhao, Xiaolan
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280569/