HOP2-MND1 modulates RAD51 binding to nucleotides and DNA
The HOP2-MND1 heterodimer is required for progression of homologous recombination in eukaryotes. In vitro, HOP2-MND1 stimulates the DNA strand exchange activities of RAD51 and DMC1. We demonstrate that HOP2-MND1 induces changes in the conformation of RAD51 that profoundly alter the basic properties...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279451/ |