Anesthesia for hemicolectomy in a known porphyric with cecal malignancy
Intraoperative management of a known acute intermittent porphyria patient is a challenge requiring awareness of factors, which trigger an acute crisis, clinical features of a porphyric attack, knowledge of safe pharmacologic intervention, and preparedness for reintubation and ventilatory support. Th...
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2015
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pubmed-42793552015-01-02 Anesthesia for hemicolectomy in a known porphyric with cecal malignancy Naithani, B. K. Shah, Shagun Bhatia Bhargava, A. K. Batra, Vivek Case Report Intraoperative management of a known acute intermittent porphyria patient is a challenge requiring awareness of factors, which trigger an acute crisis, clinical features of a porphyric attack, knowledge of safe pharmacologic intervention, and preparedness for reintubation and ventilatory support. The classical signs of a porphyric crisis such as pain abdomen, vomiting and neuropsychiatric symptoms are masked under general anesthesia and can be confused with postoperative pain and vomiting and postoperative cognitive dysfunction, especially for intra-abdominal surgeries. Eternal vigilance for onset of an acute crisis is imperative. After a crisis of acute intermittent porphyria, residual paresis may persist for years in the absence of further attacks. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4279355/ /pubmed/25558204 http://dx.doi.org/10.4103/1658-354X.146320 Text en Copyright: © Saudi Journal of Anaesthesia http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Naithani, B. K. Shah, Shagun Bhatia Bhargava, A. K. Batra, Vivek |
spellingShingle |
Naithani, B. K. Shah, Shagun Bhatia Bhargava, A. K. Batra, Vivek Anesthesia for hemicolectomy in a known porphyric with cecal malignancy |
author_facet |
Naithani, B. K. Shah, Shagun Bhatia Bhargava, A. K. Batra, Vivek |
author_sort |
Naithani, B. K. |
title |
Anesthesia for hemicolectomy in a known porphyric with cecal malignancy |
title_short |
Anesthesia for hemicolectomy in a known porphyric with cecal malignancy |
title_full |
Anesthesia for hemicolectomy in a known porphyric with cecal malignancy |
title_fullStr |
Anesthesia for hemicolectomy in a known porphyric with cecal malignancy |
title_full_unstemmed |
Anesthesia for hemicolectomy in a known porphyric with cecal malignancy |
title_sort |
anesthesia for hemicolectomy in a known porphyric with cecal malignancy |
description |
Intraoperative management of a known acute intermittent porphyria patient is a challenge requiring awareness of factors, which trigger an acute crisis, clinical features of a porphyric attack, knowledge of safe pharmacologic intervention, and preparedness for reintubation and ventilatory support. The classical signs of a porphyric crisis such as pain abdomen, vomiting and neuropsychiatric symptoms are masked under general anesthesia and can be confused with postoperative pain and vomiting and postoperative cognitive dysfunction, especially for intra-abdominal surgeries. Eternal vigilance for onset of an acute crisis is imperative. After a crisis of acute intermittent porphyria, residual paresis may persist for years in the absence of further attacks. |
publisher |
Medknow Publications & Media Pvt Ltd |
publishDate |
2015 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279355/ |
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1613171626402119680 |