Anesthesia for hemicolectomy in a known porphyric with cecal malignancy

Intraoperative management of a known acute intermittent porphyria patient is a challenge requiring awareness of factors, which trigger an acute crisis, clinical features of a porphyric attack, knowledge of safe pharmacologic intervention, and preparedness for reintubation and ventilatory support. Th...

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Main Authors: Naithani, B. K., Shah, Shagun Bhatia, Bhargava, A. K., Batra, Vivek
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279355/
id pubmed-4279355
recordtype oai_dc
spelling pubmed-42793552015-01-02 Anesthesia for hemicolectomy in a known porphyric with cecal malignancy Naithani, B. K. Shah, Shagun Bhatia Bhargava, A. K. Batra, Vivek Case Report Intraoperative management of a known acute intermittent porphyria patient is a challenge requiring awareness of factors, which trigger an acute crisis, clinical features of a porphyric attack, knowledge of safe pharmacologic intervention, and preparedness for reintubation and ventilatory support. The classical signs of a porphyric crisis such as pain abdomen, vomiting and neuropsychiatric symptoms are masked under general anesthesia and can be confused with postoperative pain and vomiting and postoperative cognitive dysfunction, especially for intra-abdominal surgeries. Eternal vigilance for onset of an acute crisis is imperative. After a crisis of acute intermittent porphyria, residual paresis may persist for years in the absence of further attacks. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4279355/ /pubmed/25558204 http://dx.doi.org/10.4103/1658-354X.146320 Text en Copyright: © Saudi Journal of Anaesthesia http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Naithani, B. K.
Shah, Shagun Bhatia
Bhargava, A. K.
Batra, Vivek
spellingShingle Naithani, B. K.
Shah, Shagun Bhatia
Bhargava, A. K.
Batra, Vivek
Anesthesia for hemicolectomy in a known porphyric with cecal malignancy
author_facet Naithani, B. K.
Shah, Shagun Bhatia
Bhargava, A. K.
Batra, Vivek
author_sort Naithani, B. K.
title Anesthesia for hemicolectomy in a known porphyric with cecal malignancy
title_short Anesthesia for hemicolectomy in a known porphyric with cecal malignancy
title_full Anesthesia for hemicolectomy in a known porphyric with cecal malignancy
title_fullStr Anesthesia for hemicolectomy in a known porphyric with cecal malignancy
title_full_unstemmed Anesthesia for hemicolectomy in a known porphyric with cecal malignancy
title_sort anesthesia for hemicolectomy in a known porphyric with cecal malignancy
description Intraoperative management of a known acute intermittent porphyria patient is a challenge requiring awareness of factors, which trigger an acute crisis, clinical features of a porphyric attack, knowledge of safe pharmacologic intervention, and preparedness for reintubation and ventilatory support. The classical signs of a porphyric crisis such as pain abdomen, vomiting and neuropsychiatric symptoms are masked under general anesthesia and can be confused with postoperative pain and vomiting and postoperative cognitive dysfunction, especially for intra-abdominal surgeries. Eternal vigilance for onset of an acute crisis is imperative. After a crisis of acute intermittent porphyria, residual paresis may persist for years in the absence of further attacks.
publisher Medknow Publications & Media Pvt Ltd
publishDate 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4279355/
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