Immunosuppression after Sepsis: Systemic Inflammation and Sepsis Induce a Loss of Naïve T-Cells but No Enduring Cell-Autonomous Defects in T-Cell Function

Immunosuppression after Sepsis: Systemic Inflammation and Sepsis Induce a Loss of Naïve T-Cells but No Enduring Cell-Autonomous Defects in T-Cell Function

Sepsis describes the life-threatening systemic inflammatory response (SIRS) of an organism to an infection and is the leading cause of mortality on intensive care units (ICU) worldwide. An acute episode of sepsis is characterized by the extensive release of cytokines and other mediators resulting in...

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Bibliographic Details
Main Authors: Markwart, Robby, Condotta, Stephanie A., Requardt, Robert P., Borken, Farina, Schubert, Katja, Weigel, Cynthia, Bauer, Michael, Griffith, Thomas S., Förster, Martin, Brunkhorst, Frank M., Badovinac, Vladimir P., Rubio, Ignacio
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277344/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277344/

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