Using common variants to indicate cancer genes

The catalogue of tumour-specific somatic mutations (SMs) is growing rapidly owing to the advent of next-generation sequencing. Identifying those mutations responsible for the development and progression of the disease, so-called driver mutations, will increase our understanding of carcinogenesis and...

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Bibliographic Details
Main Authors: Stead, Lucy F, Thygesen, Helene, Westhead, David R, Rabbitts, Pamela
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277321/