A thorough QT study in the context of an uptitration regimen with selexipag, a selective oral prostacyclin receptor agonist

A thorough QT study in the context of an uptitration regimen with selexipag, a selective oral prostacyclin receptor agonist

The effects of selexipag and its active metabolite ACT-333679 on cardiac repolarization were assessed in a thorough QT study as per International Conference on Harmonisation E14 guidance. In this randomized, double-blind, placebo/positive-controlled, parallel-group study, healthy male and female sub...

Full description

Bibliographic Details
Main Authors: Hoch, Matthias, Darpo, Borje, Remenova, Tatiana, Stoltz, Randall, Zhou, Meijian, Kaufmann, Priska, Bruderer, Shirin, Dingemanse, Jasper
Format: Online
Language:English
Published: Dove Medical Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277127/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277127/

Similar Items