Regulation of TGF-β Superfamily Signaling by SMAD Mono-Ubiquitination

TGF-β(transforming growth factor-β) superfamily signaling mediators are important regulators of diverse physiological and pathological events. TGF-β signals are transduced by transmembrane type I and type II serine/threonine kinase receptors and their downstream effectors, the SMAD (drosophila mothe...

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Bibliographic Details
Main Authors: Xie, Feng, Zhang, Zhengkui, van Dam, Hans, Zhang, Long, Zhou, Fangfang
Format: Online
Language:English
Published: MDPI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276910/