Mitochondrial DNA Aberrations and Pathophysiological Implications in Hematopoietic Diseases, Chronic Inflammatory Diseases, and Cancers
Mitochondria are important intracellular organelles that produce energy for cellular development, differentiation, and growth. Mitochondrial DNA (mtDNA) presents a 10- to 20-fold higher susceptibility to genetic mutations owing to the lack of introns and histone proteins. The mtDNA repair system is...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Korean Society for Laboratory Medicine
2015
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272938/ |