Mitochondrial DNA Aberrations and Pathophysiological Implications in Hematopoietic Diseases, Chronic Inflammatory Diseases, and Cancers

Mitochondria are important intracellular organelles that produce energy for cellular development, differentiation, and growth. Mitochondrial DNA (mtDNA) presents a 10- to 20-fold higher susceptibility to genetic mutations owing to the lack of introns and histone proteins. The mtDNA repair system is...

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Bibliographic Details
Main Authors: Kim, Hye-Ran, Won, Stephanie Jane, Fabian, Claire, Kang, Min-Gu, Szardenings, Michael, Shin, Myung-Geun
Format: Online
Language:English
Published: The Korean Society for Laboratory Medicine 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272938/