SCL, LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells

SCL, LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells

The molecular determinants that render specific populations of normal cells susceptible to oncogenic reprogramming into self-renewing cancer stem cells are poorly understood. Here, we exploit T-cell acute lymphoblastic leukemia (T-ALL) as a model to define the critical initiating events in this dise...

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Bibliographic Details
Main Authors: Gerby, Bastien, Tremblay, Cedric S., Tremblay, Mathieu, Rojas-Sutterlin, Shanti, Herblot, Sabine, Hébert, Josée, Sauvageau, Guy, Lemieux, Sébastien, Lécuyer, Eric, Veiga, Diogo F. T., Hoang, Trang
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270438/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270438/

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