Dendritic Na+ spikes enable cortical input to drive action potential output from hippocampal CA2 pyramidal neurons

Synaptic inputs from different brain areas are often targeted to distinct regions of neuronal dendritic arbors. Inputs to proximal dendrites usually produce large somatic EPSPs that efficiently trigger action potential (AP) output, whereas inputs to distal dendrites are greatly attenuated and may la...

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Bibliographic Details
Main Authors: Sun, Qian, Srinivas, Kalyan V, Sotayo, Alaba, Siegelbaum, Steven A
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270080/