The calcium stored in the sarcoplasmic reticulum acts as a safety mechanism in rainbow trout heart

Cardiomyocyte contraction depends on rapid changes in intracellular Ca2+. In mammals, Ca2+ influx as L-type Ca2+ current (ICa) triggers the release of Ca2+ from sarcoplasmic reticulum (SR) and Ca2+-induced Ca2+ release (CICR) is critical for excitation-contraction coupling. In fish, the relative con...

Full description

Bibliographic Details
Main Authors: Cros, Caroline, Sallé, Laurent, Warren, Daniel E., Shiels, Holly A., Brette, Fabien
Format: Online
Language:English
Published: American Physiological Society 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269670/