Temporal trends in prevalence of Plasmodium falciparum drug resistance alleles over two decades of changing antimalarial policy in coastal Kenya
•Genomic changes in malaria parasites over 2 decades of drug pressure were assessed.•Chloroquine-sensitive and antifolate-resistant parasite populations rose over time.•Steady increases in pfmdr1_N86 and D1246 alleles noted after chloroquine removal.•Chloroquine-sensitive parasites 15 years after it...
| Main Authors: | , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Elsevier
2014
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266795/ |