Radiofrequency ablation using BarRx for the endoscopic treatment of radiation proctopathy: a series of three cases
Radiation proctopathy is a complication of pelvic radiotherapy, which occurs in patients treated for carcinoma of the prostate, rectum, urinary bladder, cervix, uterus, and testes. If it presents within 6 weeks to 9 months after therapy, it is called acute radiation proctitis/proctopathy (ARP), and...
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Dove Medical Press
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266256/ |
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pubmed-42662562014-12-18 Radiofrequency ablation using BarRx for the endoscopic treatment of radiation proctopathy: a series of three cases Patel, Anish Pathak, Rahul Deshpande, Vrushak Patel, Sunil H Wickremesinghe, Prasanna C Vadada, Deepak Case Series Radiation proctopathy is a complication of pelvic radiotherapy, which occurs in patients treated for carcinoma of the prostate, rectum, urinary bladder, cervix, uterus, and testes. If it presents within 6 weeks to 9 months after therapy, it is called acute radiation proctitis/proctopathy (ARP), and if it occurs 9 months to a year after treatment, it is classified as chronic radiation proctitis/proctopathy (CRP). CRP occurs in 5%–20% of patients receiving pelvic radiation, depending on the radiation dose and the presence or absence of chemotherapy. In many cases, CRP resolves spontaneously, but in some, it can lead to persistent rectal bleeding. Other symptoms of CRP include diarrhea, mucoid discharge, urgency, tenesmus, rectal pain, and fecal incontinence. Despite the availability of several therapies, many patients fail to respond, and continue to suffer in their quality of life. Radiofrequency ablation (RFA) is a newer endoscopic technique that uses radiofrequency energy to ablate tissue. This is an emerging way to treat radiation proctopathy and other mucosal telangiectasia. We present three cases of radiation proctopathy treated with RFA at our institute and review the literature on treatment modalities for CRP. We were also able to find 16 other cases of CRP that used RFA, and review their literature as well as literature on other treatment modalities. Dove Medical Press 2014-12-08 /pmc/articles/PMC4266256/ /pubmed/25525377 http://dx.doi.org/10.2147/CEG.S66534 Text en © 2014 Patel et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Patel, Anish Pathak, Rahul Deshpande, Vrushak Patel, Sunil H Wickremesinghe, Prasanna C Vadada, Deepak |
| spellingShingle |
Patel, Anish Pathak, Rahul Deshpande, Vrushak Patel, Sunil H Wickremesinghe, Prasanna C Vadada, Deepak Radiofrequency ablation using BarRx for the endoscopic treatment of radiation proctopathy: a series of three cases |
| author_facet |
Patel, Anish Pathak, Rahul Deshpande, Vrushak Patel, Sunil H Wickremesinghe, Prasanna C Vadada, Deepak |
| author_sort |
Patel, Anish |
| title |
Radiofrequency ablation using BarRx for the endoscopic treatment of radiation proctopathy: a series of three cases |
| title_short |
Radiofrequency ablation using BarRx for the endoscopic treatment of radiation proctopathy: a series of three cases |
| title_full |
Radiofrequency ablation using BarRx for the endoscopic treatment of radiation proctopathy: a series of three cases |
| title_fullStr |
Radiofrequency ablation using BarRx for the endoscopic treatment of radiation proctopathy: a series of three cases |
| title_full_unstemmed |
Radiofrequency ablation using BarRx for the endoscopic treatment of radiation proctopathy: a series of three cases |
| title_sort |
radiofrequency ablation using barrx for the endoscopic treatment of radiation proctopathy: a series of three cases |
| description |
Radiation proctopathy is a complication of pelvic radiotherapy, which occurs in patients treated for carcinoma of the prostate, rectum, urinary bladder, cervix, uterus, and testes. If it presents within 6 weeks to 9 months after therapy, it is called acute radiation proctitis/proctopathy (ARP), and if it occurs 9 months to a year after treatment, it is classified as chronic radiation proctitis/proctopathy (CRP). CRP occurs in 5%–20% of patients receiving pelvic radiation, depending on the radiation dose and the presence or absence of chemotherapy. In many cases, CRP resolves spontaneously, but in some, it can lead to persistent rectal bleeding. Other symptoms of CRP include diarrhea, mucoid discharge, urgency, tenesmus, rectal pain, and fecal incontinence. Despite the availability of several therapies, many patients fail to respond, and continue to suffer in their quality of life. Radiofrequency ablation (RFA) is a newer endoscopic technique that uses radiofrequency energy to ablate tissue. This is an emerging way to treat radiation proctopathy and other mucosal telangiectasia. We present three cases of radiation proctopathy treated with RFA at our institute and review the literature on treatment modalities for CRP. We were also able to find 16 other cases of CRP that used RFA, and review their literature as well as literature on other treatment modalities. |
| publisher |
Dove Medical Press |
| publishDate |
2014 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266256/ |
| _version_ |
1613167597083164672 |