Inhibition of pathogenic non-enveloped viruses by 25-hydroxycholesterol and 27-hydroxycholesterol

Recent studies reported a broad but selective antiviral activity of 25-hydroxycholesterol (25HC) against enveloped viruses, being apparently inactive against non-enveloped viruses. Here we show that 25HC is endowed with a marked antiviral activity against three pathogenic non-enveloped viruses, i.e....

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Bibliographic Details
Main Authors: Civra, Andrea, Cagno, Valeria, Donalisio, Manuela, Biasi, Fiorella, Leonarduzzi, Gabriella, Poli, Giuseppe, Lembo, David
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265783/