High levels of SIRT1 expression enhance tumorigenesis and associate with a poor prognosis of colorectal carcinoma patients

High levels of SIRT1 expression enhance tumorigenesis and associate with a poor prognosis of colorectal carcinoma patients

SIRT1, a NAD+ dependent class III deacetylase, takes part in many important biological processes. Previous studies show that SIRT1 is overexpressed in some cancers and plays an essential role in tumorigenesis. However, the association between SIRT1 and colorectal cancer (CRC) is still unclear. We fo...

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Bibliographic Details
Main Authors: Chen, Xiaojing, Sun, Kai, Jiao, Shufan, Cai, Ning, Zhao, Xue, Zou, Hanbing, Xie, Yuexia, Wang, Zhengshi, Zhong, Ming, Wei, Lixin
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265776/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265776/

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