Cell-based Models To Investigate Tau Aggregation

Accumulation of abnormal tau aggregates in neuron is an important pathological signature in multiple neurodegenerative disorders including Alzheimer's disease. Tau is a neuron specific microtubule-associated protein that regulates microtubule stability, which is critical for axonal outgrowth an...

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Bibliographic Details
Main Authors: Lim, Sungsu, Haque, Md. Mamunul, Kim, Dohee, Kim, Dong Jin, Kim, Yun Kyung
Format: Online
Language:English
Published: Research Network of Computational and Structural Biotechnology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4262059/