The NF2 Tumor Suppressor Regulates Microtubule-Based Vesicle Trafficking via a Novel Rac, MLK and p38SAPK Pathway

The NF2 Tumor Suppressor Regulates Microtubule-Based Vesicle Trafficking via a Novel Rac, MLK and p38SAPK Pathway

Neurofibromatosis Type 2 patients develop schwannomas, meningiomas and ependymomas resulting from mutations in the tumor suppressor gene, NF2, encoding a membrane-cytoskeleton adaptor protein called merlin. Merlin regulates contact inhibition of growth and controls the availability of growth factor...

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Bibliographic Details
Main Authors: Hennigan, Robert F., Moon, Chandra A., Parysek, Linda M., Monk, Kelly R., Morfini, Gerardo, Berth, Sarah, Brady, Scott, Ratner, Nancy
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260777/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260777/

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