Glipizide, an antidiabetic drug, suppresses tumor growth and metastasis by inhibiting angiogenesis

Angiogenesis is involved in the development, progression and metastasis of various human cancers. Herein, we report the discovery of glipizide, a widely used drug for type 2 diabetes mellitus, as a promising anticancer agent through the inhibition of tumor angiogenesis. By high-throughput screening...

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Bibliographic Details
Main Authors: Qi, Cuiling, Zhou, Qin, Li, Bin, Yang, Yang, Cao, Liu, Ye, Yuxiang, Li, Jiangchao, Ding, Yi, Wang, Huiping, Wang, Jintao, He, Xiaodong, Zhang, Qianqian, Lan, Tian, Kenneth Ka Ho, Lee, Li, Weidong, Song, Xiaoyu, Zhou, Jia, Yang, Xuesong, Wang, Lijing
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259451/