Exposure to Mitochondrial Genotoxins and Dopaminergic Neurodegeneration in Caenorhabditis elegans

Neurodegeneration has been correlated with mitochondrial DNA (mtDNA) damage and exposure to environmental toxins, but causation is unclear. We investigated the ability of several known environmental genotoxins and neurotoxins to cause mtDNA damage, mtDNA depletion, and neurodegeneration in Caenorhab...

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Bibliographic Details
Main Authors: González-Hunt, Claudia P., Leung, Maxwell C. K., Bodhicharla, Rakesh K., McKeever, Madeline G., Arrant, Andrew E., Margillo, Kathleen M., Ryde, Ian T., Cyr, Derek D., Kosmaczewski, Sara G., Hammarlund, Marc, Meyer, Joel N.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259338/