Chronic Parasitic Infection Maintains High Frequencies of Short-Lived Ly6C+CD4+ Effector T Cells That Are Required for Protection against Re-infection

In contrast to the ability of long-lived CD8+ memory T cells to mediate protection against systemic viral infections, the relationship between CD4+ T cell memory and acquired resistance against infectious pathogens remains poorly defined. This is especially true for T helper 1 (Th1) concomitant immu...

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Bibliographic Details
Main Authors: Peters, Nathan C., Pagán, Antonio J., Lawyer, Phillip G., Hand, Timothy W., Henrique Roma, Eric, Stamper, Lisa W., Romano, Audrey, Sacks, David L.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256462/