Physiologically-Based Toxicokinetic Modeling of Zearalenone and Its Metabolites: Application to the Jersey Girl Study

Zearalenone (ZEA), a fungal mycotoxin, and its metabolite zeranol (ZAL) are known estrogen agonists in mammals, and are found as contaminants in food. Zeranol, which is more potent than ZEA and comparable in potency to estradiol, is also added as a growth additive in beef in the US and Canada. This...

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Bibliographic Details
Main Authors: Mukherjee, Dwaipayan, Royce, Steven G., Alexander, Jocelyn A., Buckley, Brian, Isukapalli, Sastry S., Bandera, Elisa V., Zarbl, Helmut, Georgopoulos, Panos G.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256163/