Evidence of Convergent Evolution in Humans and Macaques Supports an Adaptive Role for Copy Number Variation of the β-Defensin-2 Gene

Evidence of Convergent Evolution in Humans and Macaques Supports an Adaptive Role for Copy Number Variation of the β-Defensin-2 Gene

β-defensins are a family of important peptides of innate immunity, involved in host defense, immunomodulation, reproduction, and pigmentation. Genes encoding β-defensins show evidence of birth-and-death evolution, adaptation by amino acid sequence changes, and extensive copy number variation (CNV) w...

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Bibliographic Details
Main Authors: Ottolini, Barbara, Hornsby, Michael J., Abujaber, Razan, MacArthur, Jacqueline A.L., Badge, Richard M., Schwarzacher, Trude, Albertson, Donna G., Bevins, Charles L., Solnick, Jay V., Hollox, Edward J.
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255768/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255768/

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