CD99 Drives Terminal Differentiation of Osteosarcoma Cells by Acting as a Spatial Regulator of ERK 1/2†

CD99 Drives Terminal Differentiation of Osteosarcoma Cells by Acting as a Spatial Regulator of ERK 1/2†

Differentiation therapy is an attractive treatment for osteosarcoma (OS). CD99 is a cell surface molecule expressed in mesenchymal stem cells and osteoblasts that is maintained during osteoblast differentiation while lost in OS. Herein, we show that whenever OS cells regain CD99, they become prone t...

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Bibliographic Details
Main Authors: Sciandra, Marika, Marino, Maria Teresa, Manara, Maria Cristina, Guerzoni, Clara, Grano, Maria, Oranger, Angela, Lucarelli, Enrico, Lollini, Pier-Luigi, Dozza, Barbara, Pratelli, Loredana, Di Renzo, Maria Flavia, Colombo, Mario Paolo, Picci, Piero, Scotlandi, Katia
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255300/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255300/

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