The Epigenetic Regulator CXXC Finger Protein 1 is Essential for Murine Hematopoiesis

The Epigenetic Regulator CXXC Finger Protein 1 is Essential for Murine Hematopoiesis

CXXC finger protein 1 (Cfp1), encoded by the Cxxc1 gene, binds to DNA sequences containing an unmethylated CpG dinucleotide and is an epigenetic regulator of both cytosine and histone methylation. Cxxc1-null mouse embryos fail to gastrulate, and Cxxc1-null embryonic stem cells are viable but cannot...

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Bibliographic Details
Main Authors: Chun, Kristin T., Li, Binghui, Dobrota, Erika, Tate, Courtney, Lee, Jeong-Heon, Khan, Shehnaz, Haneline, Laura, HogenEsch, Harm, Skalnik, David G.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254612/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254612/

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