Congenital candidiasis
Congenital candidiasis (CC) is a rare disease with less than 100 cases being reported in the literature. It presents within six days of life with manifestations ranging from localized skin disease to systemic involvement in the form of respiratory distress, sepsis, and death. We report a neonate who...
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| Format: | Online |
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Medknow Publications & Media Pvt Ltd
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252951/ |
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pubmed-42529512014-12-12 Congenital candidiasis Aruna, Chintaginjala Seetharam, Kolalapudi Case Report Congenital candidiasis (CC) is a rare disease with less than 100 cases being reported in the literature. It presents within six days of life with manifestations ranging from localized skin disease to systemic involvement in the form of respiratory distress, sepsis, and death. We report a neonate who presented with diffuse pustular eruption on erythematous background involving face, trunk, and palms within 24 h after birth. Candida albicans was identified in 10% potassium hydroxide (KOH) smear and culture from the pustules. Intravenous fluconazole and topical ketoconazole were given and the condition improved completely in two weeks. CC is rare and needs to be differentiated from other conditions presenting with pustular lesions at birth in order to avoid complications. Early diagnosis and prompt treatment of this condition is important as untreated cases carry a mortality rate of 8-40%. Medknow Publications & Media Pvt Ltd 2014-11 /pmc/articles/PMC4252951/ /pubmed/25506564 http://dx.doi.org/10.4103/2229-5178.144531 Text en Copyright: © Indian Dermatology Online Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Aruna, Chintaginjala Seetharam, Kolalapudi |
| spellingShingle |
Aruna, Chintaginjala Seetharam, Kolalapudi Congenital candidiasis |
| author_facet |
Aruna, Chintaginjala Seetharam, Kolalapudi |
| author_sort |
Aruna, Chintaginjala |
| title |
Congenital candidiasis |
| title_short |
Congenital candidiasis |
| title_full |
Congenital candidiasis |
| title_fullStr |
Congenital candidiasis |
| title_full_unstemmed |
Congenital candidiasis |
| title_sort |
congenital candidiasis |
| description |
Congenital candidiasis (CC) is a rare disease with less than 100 cases being reported in the literature. It presents within six days of life with manifestations ranging from localized skin disease to systemic involvement in the form of respiratory distress, sepsis, and death. We report a neonate who presented with diffuse pustular eruption on erythematous background involving face, trunk, and palms within 24 h after birth. Candida albicans was identified in 10% potassium hydroxide (KOH) smear and culture from the pustules. Intravenous fluconazole and topical ketoconazole were given and the condition improved completely in two weeks. CC is rare and needs to be differentiated from other conditions presenting with pustular lesions at birth in order to avoid complications. Early diagnosis and prompt treatment of this condition is important as untreated cases carry a mortality rate of 8-40%. |
| publisher |
Medknow Publications & Media Pvt Ltd |
| publishDate |
2014 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252951/ |
| _version_ |
1613163268078043136 |