Combining Motion Analysis and Microfluidics – A Novel Approach for Detecting Whole-Animal Responses to Test Substances

Small, early life stages, such as zebrafish embryos are increasingly used to assess the biological effects of chemical compounds in vivo. However, behavioural screens of such organisms are challenging in terms of both data collection (culture techniques, drug delivery and imaging) and data evaluatio...

Full description

Bibliographic Details
Main Authors: Rudin-Bitterli, Tabitha S., Tills, Oliver, Spicer, John I., Culverhouse, Phil F., Wielhouwer, Eric M., Richardson, Michael K., Rundle, Simon D.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251981/