Gyejigachulbu-Tang Relieves Oxaliplatin-Induced Neuropathic Cold and Mechanical Hypersensitivity in Rats via the Suppression of Spinal Glial Activation

Activation of spinal glial cells plays a crucial role in the pathogenesis of neuropathic pain. An administration of oxaliplatin, an important anticancer drug, often induces acute neuropathic cold hypersensitivity and/or mechanical hypersensitivity in patients. Gyejigachulbu-tang (GBT), a herbal form...

Full description

Bibliographic Details
Main Authors: Ahn, Byung-Soo, Kim, Seong-Kyu, Kim, Ha Neul, Lee, Ji-Hye, Lee, Ji-Hwan, Hwang, Deog Sang, Bae, Hyunsu, Min, Byung-Il, Kim, Sun Kwang
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251814/