TP53/p53 alterations and Aurora A expression in progressor and non-progressor colectomies from patients with longstanding ulcerative colitis

Aneuploidy is a common feature in the colonic mucosa of patients suffering from the inflammatory bowel disease ulcerative colitis (UC) and often precedes the development of dysplasia and cancer. Aneuploidy is assumed to be caused by missegregation of chromosomes during mitosis, often due to a faulty...

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Bibliographic Details
Main Authors: FRIIS-OTTESSEN, MARIANN, BURUM-AUENSEN, ESPEN, SCHJØLBERG, AASA R., EKSTRØM, PER OLAF, ANDERSEN, SOLVEIG N., CLAUSEN, OLE PETTER, DE ANGELIS, PAULA M.
Format: Online
Language:English
Published: D.A. Spandidos 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249752/