Nomenclature- and Database-Compatible Names for the Two Ebola Virus Variants that Emerged in Guinea and the Democratic Republic of the Congo in 2014
In 2014, Ebola virus (EBOV) was identified as the etiological agent of a large and still expanding outbreak of Ebola virus disease (EVD) in West Africa and a much more confined EVD outbreak in Middle Africa. Epidemiological and evolutionary analyses confirmed that all cases of both outbreaks are con...
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| Format: | Online |
| Language: | English |
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MDPI
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246247/ |
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pubmed-42462472014-12-01 Nomenclature- and Database-Compatible Names for the Two Ebola Virus Variants that Emerged in Guinea and the Democratic Republic of the Congo in 2014 Kuhn, Jens H. Andersen, Kristian G. Baize, Sylvain Bào, Yīmíng Bavari, Sina Berthet, Nicolas Blinkova, Olga Brister, J. Rodney Clawson, Anna N. Fair, Joseph Gabriel, Martin Garry, Robert F. Gire, Stephen K. Goba, Augustine Gonzalez, Jean-Paul Günther, Stephan Happi, Christian T. Jahrling, Peter B. Kapetshi, Jimmy Kobinger, Gary Kugelman, Jeffrey R. Leroy, Eric M. Maganga, Gael Darren Mbala, Placide K. Moses, Lina M. Muyembe-Tamfum, Jean-Jacques N’Faly, Magassouba Nichol, Stuart T. Omilabu, Sunday A. Palacios, Gustavo Park, Daniel J. Paweska, Janusz T. Radoshitzky, Sheli R. Rossi, Cynthia A. Sabeti, Pardis C. Schieffelin, John S. Schoepp, Randal J. Sealfon, Rachel Swanepoel, Robert Towner, Jonathan S. Wada, Jiro Wauquier, Nadia Yozwiak, Nathan L. Formenty, Pierre Letter In 2014, Ebola virus (EBOV) was identified as the etiological agent of a large and still expanding outbreak of Ebola virus disease (EVD) in West Africa and a much more confined EVD outbreak in Middle Africa. Epidemiological and evolutionary analyses confirmed that all cases of both outbreaks are connected to a single introduction each of EBOV into human populations and that both outbreaks are not directly connected. Coding-complete genomic sequence analyses of isolates revealed that the two outbreaks were caused by two novel EBOV variants, and initial clinical observations suggest that neither of them should be considered strains. Here we present consensus decisions on naming for both variants (West Africa: “Makona”, Middle Africa: “Lomela”) and provide database-compatible full, shortened, and abbreviated names that are in line with recently established filovirus sub-species nomenclatures. MDPI 2014-11-24 /pmc/articles/PMC4246247/ /pubmed/25421896 http://dx.doi.org/10.3390/v6114760 Text en © 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
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NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Kuhn, Jens H. Andersen, Kristian G. Baize, Sylvain Bào, Yīmíng Bavari, Sina Berthet, Nicolas Blinkova, Olga Brister, J. Rodney Clawson, Anna N. Fair, Joseph Gabriel, Martin Garry, Robert F. Gire, Stephen K. Goba, Augustine Gonzalez, Jean-Paul Günther, Stephan Happi, Christian T. Jahrling, Peter B. Kapetshi, Jimmy Kobinger, Gary Kugelman, Jeffrey R. Leroy, Eric M. Maganga, Gael Darren Mbala, Placide K. Moses, Lina M. Muyembe-Tamfum, Jean-Jacques N’Faly, Magassouba Nichol, Stuart T. Omilabu, Sunday A. Palacios, Gustavo Park, Daniel J. Paweska, Janusz T. Radoshitzky, Sheli R. Rossi, Cynthia A. Sabeti, Pardis C. Schieffelin, John S. Schoepp, Randal J. Sealfon, Rachel Swanepoel, Robert Towner, Jonathan S. Wada, Jiro Wauquier, Nadia Yozwiak, Nathan L. Formenty, Pierre |
| spellingShingle |
Kuhn, Jens H. Andersen, Kristian G. Baize, Sylvain Bào, Yīmíng Bavari, Sina Berthet, Nicolas Blinkova, Olga Brister, J. Rodney Clawson, Anna N. Fair, Joseph Gabriel, Martin Garry, Robert F. Gire, Stephen K. Goba, Augustine Gonzalez, Jean-Paul Günther, Stephan Happi, Christian T. Jahrling, Peter B. Kapetshi, Jimmy Kobinger, Gary Kugelman, Jeffrey R. Leroy, Eric M. Maganga, Gael Darren Mbala, Placide K. Moses, Lina M. Muyembe-Tamfum, Jean-Jacques N’Faly, Magassouba Nichol, Stuart T. Omilabu, Sunday A. Palacios, Gustavo Park, Daniel J. Paweska, Janusz T. Radoshitzky, Sheli R. Rossi, Cynthia A. Sabeti, Pardis C. Schieffelin, John S. Schoepp, Randal J. Sealfon, Rachel Swanepoel, Robert Towner, Jonathan S. Wada, Jiro Wauquier, Nadia Yozwiak, Nathan L. Formenty, Pierre Nomenclature- and Database-Compatible Names for the Two Ebola Virus Variants that Emerged in Guinea and the Democratic Republic of the Congo in 2014 |
| author_facet |
Kuhn, Jens H. Andersen, Kristian G. Baize, Sylvain Bào, Yīmíng Bavari, Sina Berthet, Nicolas Blinkova, Olga Brister, J. Rodney Clawson, Anna N. Fair, Joseph Gabriel, Martin Garry, Robert F. Gire, Stephen K. Goba, Augustine Gonzalez, Jean-Paul Günther, Stephan Happi, Christian T. Jahrling, Peter B. Kapetshi, Jimmy Kobinger, Gary Kugelman, Jeffrey R. Leroy, Eric M. Maganga, Gael Darren Mbala, Placide K. Moses, Lina M. Muyembe-Tamfum, Jean-Jacques N’Faly, Magassouba Nichol, Stuart T. Omilabu, Sunday A. Palacios, Gustavo Park, Daniel J. Paweska, Janusz T. Radoshitzky, Sheli R. Rossi, Cynthia A. Sabeti, Pardis C. Schieffelin, John S. Schoepp, Randal J. Sealfon, Rachel Swanepoel, Robert Towner, Jonathan S. Wada, Jiro Wauquier, Nadia Yozwiak, Nathan L. Formenty, Pierre |
| author_sort |
Kuhn, Jens H. |
| title |
Nomenclature- and Database-Compatible Names for the Two Ebola Virus Variants that Emerged in Guinea and the Democratic Republic of the Congo in 2014 |
| title_short |
Nomenclature- and Database-Compatible Names for the Two Ebola Virus Variants that Emerged in Guinea and the Democratic Republic of the Congo in 2014 |
| title_full |
Nomenclature- and Database-Compatible Names for the Two Ebola Virus Variants that Emerged in Guinea and the Democratic Republic of the Congo in 2014 |
| title_fullStr |
Nomenclature- and Database-Compatible Names for the Two Ebola Virus Variants that Emerged in Guinea and the Democratic Republic of the Congo in 2014 |
| title_full_unstemmed |
Nomenclature- and Database-Compatible Names for the Two Ebola Virus Variants that Emerged in Guinea and the Democratic Republic of the Congo in 2014 |
| title_sort |
nomenclature- and database-compatible names for the two ebola virus variants that emerged in guinea and the democratic republic of the congo in 2014 |
| description |
In 2014, Ebola virus (EBOV) was identified as the etiological agent of a large and still expanding outbreak of Ebola virus disease (EVD) in West Africa and a much more confined EVD outbreak in Middle Africa. Epidemiological and evolutionary analyses confirmed that all cases of both outbreaks are connected to a single introduction each of EBOV into human populations and that both outbreaks are not directly connected. Coding-complete genomic sequence analyses of isolates revealed that the two outbreaks were caused by two novel EBOV variants, and initial clinical observations suggest that neither of them should be considered strains. Here we present consensus decisions on naming for both variants (West Africa: “Makona”, Middle Africa: “Lomela”) and provide database-compatible full, shortened, and abbreviated names that are in line with recently established filovirus sub-species nomenclatures. |
| publisher |
MDPI |
| publishDate |
2014 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4246247/ |
| _version_ |
1613161549840515072 |