Metabolic Profiling of Alternative NAD Biosynthetic Routes in Mouse Tissues

NAD plays essential redox and non-redox roles in cell biology. In mammals, its de novo and recycling biosynthetic pathways encompass two independent branches, the “amidated” and “deamidated” routes. Here we focused on the indispensable enzymes gating these two routes, i.e. nicotinamide mononucleotid...

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Bibliographic Details
Main Authors: Mori, Valerio, Amici, Adolfo, Mazzola, Francesca, Di Stefano, Michele, Conforti, Laura, Magni, Giulio, Ruggieri, Silverio, Raffaelli, Nadia, Orsomando, Giuseppe
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244216/