Loss of the Sec1/Munc18-family proteins VPS-33.2 and VPS-33.1 bypasses a block in endosome maturation in Caenorhabditis elegans

Evidence is presented for the existence of HOPS and CORVET tethering complexes in metazoans. A role is shown for the SM protein components of tethers in controlling the flux of material through the endosomal system.

Bibliographic Details
Main Authors: Solinger, Jachen A., Spang, Anne
Format: Online
Language:English
Published: The American Society for Cell Biology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244200/