Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter
The ATP-binding cassette (ABC) transporter associated with antigen processing (TAP) participates in immune surveillance by moving proteasomal products into the endoplasmic reticulum (ER) lumen for major histocompatibility complex class I loading and cell surface presentation to cytotoxic T cells. He...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Nature Pub. Group
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242082/ |