Chronic Idiopathic Neutrophilia in Two Twins

Neutrophilia in adults refers to an alteration in the total number of blood neutrophils that is in excess of about 7500 cells/μL. This definition is restrictive in childhood as neutrophil count is age-dependent. Chronic Idiopathic Neutrophilia (CIN) refers to a condition that persists for many years...

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Main Authors: Miniero, Roberto, Mazza, Giuseppe Antonio, Altomare, Federica, Fusaro, Carla
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241303/
id pubmed-4241303
recordtype oai_dc
spelling pubmed-42413032014-11-27 Chronic Idiopathic Neutrophilia in Two Twins Miniero, Roberto Mazza, Giuseppe Antonio Altomare, Federica Fusaro, Carla Case Report Neutrophilia in adults refers to an alteration in the total number of blood neutrophils that is in excess of about 7500 cells/μL. This definition is restrictive in childhood as neutrophil count is age-dependent. Chronic Idiopathic Neutrophilia (CIN) refers to a condition that persists for many years in individuals who appear otherwise healthy. CIN is rarely mentioned in scientific literature and in academic books of hematology; only few words are dedicated to this topic. We report a case study of two twins with CIN followed from the first year of life to 24 years of age. To the best of our knowledge this is the first case report of two twins with CIN followed through a long period of time. We believe that our observation may contribute to better understand and characterize this hematologic abnormality. Hindawi Publishing Corporation 2014 2014-11-06 /pmc/articles/PMC4241303/ /pubmed/25431700 http://dx.doi.org/10.1155/2014/785454 Text en Copyright © 2014 Roberto Miniero et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Miniero, Roberto
Mazza, Giuseppe Antonio
Altomare, Federica
Fusaro, Carla
spellingShingle Miniero, Roberto
Mazza, Giuseppe Antonio
Altomare, Federica
Fusaro, Carla
Chronic Idiopathic Neutrophilia in Two Twins
author_facet Miniero, Roberto
Mazza, Giuseppe Antonio
Altomare, Federica
Fusaro, Carla
author_sort Miniero, Roberto
title Chronic Idiopathic Neutrophilia in Two Twins
title_short Chronic Idiopathic Neutrophilia in Two Twins
title_full Chronic Idiopathic Neutrophilia in Two Twins
title_fullStr Chronic Idiopathic Neutrophilia in Two Twins
title_full_unstemmed Chronic Idiopathic Neutrophilia in Two Twins
title_sort chronic idiopathic neutrophilia in two twins
description Neutrophilia in adults refers to an alteration in the total number of blood neutrophils that is in excess of about 7500 cells/μL. This definition is restrictive in childhood as neutrophil count is age-dependent. Chronic Idiopathic Neutrophilia (CIN) refers to a condition that persists for many years in individuals who appear otherwise healthy. CIN is rarely mentioned in scientific literature and in academic books of hematology; only few words are dedicated to this topic. We report a case study of two twins with CIN followed from the first year of life to 24 years of age. To the best of our knowledge this is the first case report of two twins with CIN followed through a long period of time. We believe that our observation may contribute to better understand and characterize this hematologic abnormality.
publisher Hindawi Publishing Corporation
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241303/
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