Up-Regulation of FOXM1 by E6 Oncoprotein through the MZF1/NKX2-1 Axis Is Required for Human Papillomavirus–Associated Tumorigenesis12

PURPOSE: Foxhead box M1 (FOXM1) expression has been shown to be linked with human papillomavirus (HPV) 16/18–infected cervical cancer. However, the mechanism underlying the induction of FOXM1 in HPV 16/18–infected cancers remains elusive. EXPERIMENTAL DESIGN: The mechanistic actions of FOXM1 induced...

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Bibliographic Details
Main Authors: Chen, Po-Ming, Cheng, Ya-Wen, Wang, Yao-Chen, Wu, Tzu-Chin, Chen, Chih-Yi, Lee, Huei
Format: Online
Language:English
Published: Neoplasia Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240922/