A Biophysical Study with Carbohydrate Derivatives Explains the Molecular Basis of Monosaccharide Selectivity of the Pseudomonas aeruginosa Lectin LecB
The rise of resistances against antibiotics in bacteria is a major threat for public health and demands the development of novel antibacterial therapies. Infections with Pseudomonas aeruginosa are a severe problem for hospitalized patients and for patients suffering from cystic fibrosis. These bacte...
Main Authors: | Sommer, Roman, Exner, Thomas E., Titz, Alexander |
---|---|
Format: | Online |
Language: | English |
Published: |
Public Library of Science
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240550/ |
Similar Items
-
Cinnamide Derivatives of d‐Mannose as Inhibitors of the Bacterial Virulence Factor LecB from Pseudomonas aeruginosa
†
by: Sommer, Roman, et al.
Published: (2015) -
Specific Association of Lectin LecB with the Surface of Pseudomonas aeruginosa: Role of Outer Membrane Protein OprF
by: Funken, Horst, et al.
Published: (2012) -
Pseudomonas aeruginosa lectin LecB inhibits tissue repair processes by triggering β-catenin degradation
by: Cott, Catherine, et al.
Published: (2016) -
Genomic Rearrangements and Functional Diversification of lecA and lecB Lectin-Coding Regions Impacting the Efficacy of Glycomimetics Directed against Pseudomonas aeruginosa
by: Boukerb, Amine M., et al.
Published: (2016) -
A glycopeptide dendrimer inhibitor of the galactose specific lectin LecA & of Pseudomonas aeruginosa biofilms
by: Kadam, Rameshwar U., et al.
Published: (2011)