Evasin-4, a tick-derived chemokine-binding protein with broad selectivity can be modified for use in preclinical disease models

Rhipicephalus sanguineus, the common brown dog tick, produces several chemokine-binding proteins which are secreted into the host in its saliva to modulate the host response during feeding. Two of these demonstrate very restricted selectivity profiles. Here, we describe the characterization of the t...

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Bibliographic Details
Main Authors: Déruaz, Maud, Bonvin, Pauline, Severin, India C, Johnson, Zoë, Krohn, Sonja, Power, Christine A, Proudfoot, Amanda E I
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240464/