Drug discovery for Chagas disease should consider Trypanosoma cruzi strain diversity
This opinion piece presents an approach to standardisation of an important aspect of Chagas disease drug discovery and development: selecting Trypanosoma cruzi strains for in vitro screening. We discuss the rationale for strain selection representing T. cruzi diversity and provide recommendations on...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Instituto Oswaldo Cruz, Ministério da Saúde
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238778/ |