The role of telomeres and telomerase in hematologic malignancies and hematopoietic stem cell transplantation
Telomeres are specific nucleoprotein structures at the ends of eukaryotic chromosomes. Telomeres and telomere-associated proteins maintain genome stability by protecting the ends of chromosomes from fusion and degradation. In normal somatic cells, the length of the telomeres gradually becomes shorte...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
BioMed Central
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237881/ |