The role of telomeres and telomerase in hematologic malignancies and hematopoietic stem cell transplantation

Telomeres are specific nucleoprotein structures at the ends of eukaryotic chromosomes. Telomeres and telomere-associated proteins maintain genome stability by protecting the ends of chromosomes from fusion and degradation. In normal somatic cells, the length of the telomeres gradually becomes shorte...

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Bibliographic Details
Main Authors: Wang, Limengmeng, Xiao, Haowen, Zhang, Xing, Wang, Chong, Huang, He
Format: Online
Language:English
Published: BioMed Central 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237881/